Genomic Mismatch at LIMS1 Locus and Kidney Allograft Rejection
نویسندگان
چکیده
منابع مشابه
Rejection of the kidney allograft.
Copyright © 2010 Massachusetts Medical Society. The science of kidney transplantation has progressed considerably in the past half-century largely because of an improved understanding of the role of the immune system in allograft rejection, the disentanglement of the molecular mechanisms underlying graft failure, and better management of immunosuppression.1,2 Rejection has always been the major...
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Successful kidney transplantation improves the quality of life and increases survival when compared with long-term dialysis. Renal transplantation is now a well established and the preferred treatment for most patients with end-stage renal disease (ESRD). In recent years, the short-term effects of kidney transplantation have been greatly achieved due to the improvement in immunosuppression medi...
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Rejection of the transplanted kidney in humans is still a major cause of morbidity and mortality. The mouse model of renal transplantation closely replicates both the technical and pathological processes that occur in human renal transplantation. Although mouse models of allogeneic rejection in organs other than the kidney exist, and are more technically feasible, there is evidence that differe...
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1 Department of Urology, the First Affiliated Hospital, Chongqing Medical University, Chongqing, 400016, China. 2 Department of Emergency, the First Affiliated Hospital, Chongqing Medical University, Chongqing, 400016, China. 3 Department of Laboratory Medicine, the First Affiliated Hospital, Chongqing Medical University, Chongqing, 400016, China. *Corresponding author. E-mail: wu_yi2012@gmail....
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introduction: due to its immunosuppressive properties, local graft irradiation (lgi) has been proposed as a second line therapy for treatment of acute kidney rejection. case presentation: in this case-series we report 6 patients with biopsy proven acute kidney allograft rejection refractory to conventional antirejection therapy who underwent lgi for treatment of acute rejection at our center. t...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2019
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmoa1803731